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Methadone is a prescribed drug supplied on the Bigpharmausa website. It is an effective medication used to cure chronic or acute pain but people also buy Methadone online to suppress withdrawal symptoms caused by stopping other opioid medications.

How to Buy Methadone Online?

Methadone medication is conveniently sold under the trade name Methadose and Dolophine. For easy accessibility, it is supplied online by various telemedicine providers. Now you can buy Methadone online with a single click from any device.

To buy Methadone online from Big pharma USA, follow these steps:

  • Visit the official website ‘Big pharma USA’.
  • Then click on the ‘Shop’ option.
  • Next search for the ‘Pain Relief’ category.
  • Followed by clicking on the ‘Buy Methadone Online’ option.
  • From the ‘Buy Methadone Online’ page, choose the desired dose and quantity according to the prescription.
  • Finally, click on ‘Add to Cart’ to place an order of Methadone.

About Methadone

Methadone is a researched and man-made opioid that is similar to morphine or Heroin. It produces feelings of relaxation and reduces pain, without any of the high or euphoric effects of Heroin.

Methadone is primarily used for treating chronic muscle spasms. It is a long-acting medicine that treats Heroin addiction by reducing withdrawal symptoms and cravings. Being long-acting means it will stay active in your body for a longer time as compared to morphine or Heroin.

How Methadone Works

Methadone medicine works by altering how the brain responds to or reacts to pain sensation. It also helps in lessening the painful symptoms of opiate withdrawal by blocking the euphoric effects of opiate drugs such as Heroin, Morphine, and Codeine, as well as semi-synthetic opioids like Oxycodone and Hydrocodone.

Methadone is supplied in the form of pills, liquid solution, and wafers and is usually taken once a day. The pain relief from a dose of Methadone medicine can last about 4-8 hours.

Similar to all medications used in medication-assisted treatment (MAT), Methadone is to be prescribed as a part of a comprehensive treatment plan including proper counseling and participation in social support programs.


It takes Methadone to reach its peak effect after within 2 hours of ingestion. During the starting phase of the treatment, the effects may only last for a few hours.

The dose is gradually incremented each day as needed until the withdrawal symptoms are faded. Once the dosage is stabilized, a single Methadone medication can work for 24 to 36 hours.

Generally, Methadone tablets are available in two variants:

Proper Usage and Dosage

The effects of Methadone last much longer as compared to that of Heroin. A single dose can last for about 24 hours, whereas a dose of Heroin may only last a few hours. Methadone affects differently depending on:

  • size, weight, and health of the person
  • whether the person is used to it
  • whether other drugs are taken at the same time
  • the amount of medication taken

Dosage for Short-Term Severe Pain

Typical a starting dosage of 2.5 mg is indicated. It is taken every 8 to 12 hours.

Dosage for Opioid Addiction Management

A 20-30 mg dose of Methadone is introduced to the patient. For short-term detoxification, Methadone is taken two twice a day for 2 to 3 days. The maximum dosage should not exceed 40 mg.

Maintenance Dose for Opioid Addiction

A standard Methadone dosage ranging between 80-120 mg per day is recommended. Your doctor will determine a dosage that is appropriate for you.

Advantages of Methadone Maintenance over Heroin

  • Methadone maintenance dose keeps the patient stable
  • Health problems are reduced for those related to injecting, such as HIV, hepatitis B, hepatitis C viruses, skin infections, and vein problems
  • Methadone doses are required only once a day, due to its long-lasting effects
  • The price of Methadone is way lower than Heroin

The Methadone maintenance treatment is continued for a minimum period of 12 months. And some opioid-addict individuals continue to benefit from this treatment method for many years.

Side Effects of Methadone

  • Sweating and dehydration
  • Difficulty while urinating
  • Loss of appetite, nauseaAbdominal cramps
  • Constipation
  • Aching in muscles and joints
  • Irregular periods
  • Low sex drive
  • Rashes, hives, and itching
  • Lethargy and confusion
  • Difficulty in breathing
  • Feel lightheaded
  • Swelling of the face, lips, tongue, or throat
  • Chest pain
  • Experience a fast or pounding heartbeat
  • Hallucinations

If any of these symptoms or side effects are observed for a prolonged time, then immediately inform the doctor and take his advice as soon as possible.

Dose-Related Effects

In certain cases, it is found that few people on Methadone treatment programs experience unwanted symptoms. Particularly during the beginning stages due to their dosage not being adequate. When the dose of Methadone is too low, the following symptoms may be observed:

  • Runny nose
  • Drowsiness
  • Rise in body temperature but shivering due to cold
  • Irritability and agitation
  • Loss of appetite, nausea, and vomiting
  • Abdominal cramps and diarrhea
  • Tremors and shaking
  • Backaches
  • Cravings and urges for the drug

Overdose Symptoms

  • Depressed breathing
  • Stupor or coma
  • Severe constipation with difficulty while urinating
  • Marked allergic reaction with swelling of the face, lips, tongue, and throat
  • Intense rashes along with itching, etc.

Methadone’s Interaction with Other Drugs

Many other drugs can be dangerous when used with opioid medicine like Methadone. Before using Methadone, the concerned doctor must be informed about any of the following mentioned medications:

  • Medicine for allergies, asthma, blood pressure, motion sickness, etc.
  • Opioid medicines
  • Benzodiazepine sedatives like Valium, Klonopin, or Xanax
  • Sleep medicine, muscle relaxers, or other drugs that can make you drowsy
  • Drugs that affect serotonin, such as antidepressants, stimulants, etc.
  • Antidepressants medications (particularly monoamine oxidase inhibitors such as tranylcypromine, phenelzine, and isocarboxazid)
  • Medicines for anxiety management, such as Lorazepam and Diazepam
  • Medicine for heart rhythm problems, such as amiodarone, verapamil, diltiazem
  • Medicines for infections, including fungal infections
  • HIV medicines
  • Epilepsy medicine
  • Medicines for Parkinson’s disease

While buying Methadone online or from any medical store, always keep in mind the prescription is meant for your betterment. Never try to alter the prescription and only allow the concerned doctor to make the required changes whenever needed.