Modafinil and Adderall are the two medicines, which treat several symptoms that occur in people. These symptoms include Attentive Deficit Hyperactivity Disorder (ADHD), narcolepsy, etc. Narcolepsy is a sleeping problem, which causes sleeping attacks in individuals. Both these medicines play a different role in the treatment of problems. The applications and properties of both these medicines are the same. Now, we are going to provide brief information on Modafinil vs Adderall medicine their side effects, uses, and dosages.
Brief Overview of Modafinil Medicine
A medicine that promotes wakefulness and alertness in people is called modafinil medicine. It is approved by the Food and Drug Administration (FDA) for the treatment of sleeping problems, which include hypopnea, narcolepsy, etc.
Properties of Modafinil Medicine
The physical properties of modafinil medicine are the following:
- The molecular weight of this medicine is 273.4 g/mol.
- It is a white-colored medicine.
- Its melting point is 165 degrees Celsius and its boiling point is 50 degrees Celsius.
- It is soluble in methanol and acetone but insoluble in cyclohexane and water.
Brief Overview of Adderall Medicine
The combination of amphetamine and dextroamphetamine is called Adderall. This medicine is approved by the Food and Drug Administration for the treatment of sleeping problems and Attentive Deficit Hyperactivity Disorder (ADHD). This medicine is not used to treat elder patients or 3-year-old children.
Properties of Adderall Medicine
The physical properties of Adderall medicine are as follows:
- Its molar mass is 135.21 g/mol.
- It is colorless and has a strong characteristic odor.
- Its melting point is 25 degrees Celsius and its boiling point is 64.7 degrees Celsius.
- It is slightly soluble in chloroform, ethanol, and water.
Comparison Between Modafinil and Adderall Medicine
Below are the comparisons between Modafinil and Adderall medicine. These are as follows:
1. Approval of Food and Drug Administration
a. Modafinil
Modafinil was first approved by the Food and Drug Administration (FDA) on December 24, 1998.
b. Adderall
Adderall was first approved by the Food and Drug Administration (FDA) on January 19, 1960.
2. Brand names
a. Modafinil
Provigil is the only brand name of Modafinil.
b. Adderall
The brand names of Adderall include Mydayis and Adderall XR.
3. Dosages
a. Modafinil
A 200mg or 400mg dosage of modafinil is taken for the treatment of narcolepsy, insomnia, hypopnea, etc. The dosage is available in the form of tablets.
A 200mg modafinil is taken by adults and children above 17 years of age. Children below 17 years must take a doctor’s prescription while taking this medicine.
b. Adderall
The dosages of Adderall and Adderall XR are taken for the treatment of Narcolepsy and Attentive Deficit Hyperactivity Disorder (ADHD). They are available in the form of capsules and tablets.
The dosages of Adderall consist of 5mg, 7.5mg, 10mg, 15mg, 12.5mg, 20 mg, and 30mg tablets. 5mg tablets are taken once or twice a day by children above six years, and 2.5mg tablets per day are taken by children between 3 to 5 years of age.
The Adderall XR dosages include 20mg, 30mg, 25mg, 5mg, 10mg, and 15mg capsules. One 20mg tablet will be taken once a day by the adults and one 10mg tablet per day is taken by the children between 6 to 17 years of age.
4. Functions
a. Modafinil
Modafinil medicine controls the central part of the nervous system for sleeping problems and wakefulness in individuals. It reduces Gamma-Amino Butyric Acid (GABA) and protects neurons in the brain from damage.
b. Adderall
The function of Adderall is to control the brain with two medicinal drugs. These medicinal drugs are norepinephrine and dopamine. This helps people to control behavioral problems, improve listening skills, stay focused on their activities, and pay attention.
5. Half-life
a. Modafinil
The half-life of modafinil is 15 hours.
b. Adderall
The half-life of Adderall is 34 hours.
6. Ratings and Reviews
a. Modafinil
The average rating of modafinil is 7.2. It is reviewed by 510 people, in which 64% of them report positive feedback and 19% of them report negative feedback.
b. Adderall
The average rating of Adderall is 7.4. It is reviewed by 467 people, of which 65% of them report positive feedback, whereas 17% of them report negative feedback.
7. Drug Interactions
a. Modafinil
Small Drugs
Modafinil interacts with small medicinal drugs such as danazol, naloxegol, nefazodone, progesterone, prednisone, vincristine, vinorelbine, ziprasidone, troleandomycin, etc.
Medium Drugs
Modafinil interacts with medium medicinal drugs. These drugs include clomipramine, cyclosporine, ceritinib, gefitinib, glasdegib, infragatinib, salametrol, somatrem, etc.
Large Drugs
The interactions of modafinil with large medicinal drugs include oxycodone, hydrocodone, lumateperone, lefamulin, leniolisib, methadone, mobocertinib, etc.
b. Adderall
Small Drugs
The interactions of Adderall with small medicinal drugs are colchicine, lithium, phenytoin, phenobarbital, ethosuximide, apraclonidine ophthalmic, aromadafinil, colchicine, and evening primrose.
Medium Drugs
Modafinil has interacted with medium medicinal drugs. These drugs include bitolterol, cinacalcet, doxepin, guanethidine, liothyronine, methadone, isoproterenol, rolapitant, tirzepatide, etc.
Large Drugs
The interactions of modafinil with large medicinal drugs include tapentadol, vortioxetine, safinamide, procarbazine, levomilnacipran, isocarboxazid, furazolidone etc.
8. Side Effects
a. Modafinil
The side effects of Modafinil are as follows:
- Sore throat
- Chest pain
- Urine problem
- Dizziness
- Drowsiness
- Memory problem
- Confusion
- Blurred vision
- Fever
- Back pain
- Swelling
- Vomiting
b. Adderall
The side effects of Adderall include the following:
- Headache
- Heartburn
- Digestion problem
- Stomach pain
- High blood pressure
- Sleeping problem
- Nausea
- Nervousness
- Anxiety
- Skin and mouth dryness
9. Uses
a. Modafinil
Modafinil is used to treat the symptoms of sleeping problems or narcolepsy, Attentive Deficit Hyperactivity Disorder (ADHD), bipolar disorder, and fatigue in individuals.
b. Adderall
Adderall is used for treating symptoms of Attentive Deficit Hyperactivity Disorder (ADHD), depression, chronic fatigue, and sleeping problems or narcolepsy in people.
Conclusion
This blog describes the comparison of two medicines, which are Adderall and Modafinil. These medicines consist of several dosages and medicinal drugs for the treatment of ADHD symptoms and narcolepsy.
These medicines also cause side effects such as headache, nausea, etc. You must consult with a doctor if you are experiencing these side effects.